You have to be kind of careful. For the complex numbers, there is no problem as BCnrd wrote above. For a general field $K$, you are asking a basic question from the field of geometric algebra (there's an AMS GTM volume by Grove on the topic, and Dieudonne's books on classical groups).
If you take a nondegenerate quadratic form $q$, then we know:
- If $q$ is isotropic over $K$, then $Spin(q)(K)$ is "projectively simple" (i.e., the quotient by its finite center is simple)
- If $q$ is anisotropic, then $Spin(q)(K)$ can be far from simple. You can construct examples using valuations, as you suggest.
But you asked about $SO(q)(K)$. Then you use Galois cohomology (where I assume that $K$ has characteristic different from 2 for simplicity):
$1 \to \mu_2(K) \to Spin(q)(K) \to SO(q)(K) \to K^{\times}/K^{\times 2}$
where the last map is the spinor norm. You should think of the spinor norm as usually having a big image, so $SO(q)(K)$ will be pretty far from simple.
Your specific group
You asked specifically about $SO(q)$ where $q$ is a sum of squares. Then the spinor norm map has image products of sums of squares (typically not actually squares themselves), so you should expect the image of $Spin(q)(K)$ to be a normal subgroup in $SO(q)(K)$ of large index. (That is all very imprecise, but a precise answer depends on the arithmetic of $K$ and the dimension of $q$.) But now you can ask: Is $Spin(q)(K)$ modulo its center a simple group?
Here you have a strong advantage. If $q$ is isotropic over $K$ (i.e., you can write $0$ as a sum of a small enough number of nonzero squares), then you know from classical results that the answer is "yes".
If $q$ is not isotropic over $K$, then $Spin(q)$ is anisotropic (as an algebraic group) but it is split by the quadratic extension $K(\sqrt{-1})$. For such groups, under some hypotheses on $K$ (maybe as weak as characteristic zero), you know that the answer is again "yes" by Chernousov. See Theorem 9.7 on page 514 of the book "Algebra & Number Theory" by Platonov and Rapinchuk. You will have to inspect the proof (which starts on p.546) to see the precise hypotheses they need on $K$, or you can consult some of the original papers, where the proof is slightly different.