(Sorry for missing the "$G$ stabilizes $\Gamma_1$" condition in the previous edit)
The answer is no. The smallest counter-example: considerConsider $\Gamma = K_3$, ans$\Gamma = ([4], \{12, 13, 23, 14\})$. $G$ stabilizes $\Gamma_1$ induced by a pair of vertices. In this case= the edge $G = S_3$ and has size 6,$14$. $G_0$ is trivial$G_0 = G$, and $|G_1| = 2$, while for the semiderict product we must have $|N \rtimes H| = |N| \times |H|$.