A unary relation. Suppose $M$ is a structure in the language $\{U\}$ containing a single unary relation. Then we can form a new $\{R\}$-structure $N$, whose domain is that of $M$ and so that $R^N=\{(a, a): M\models U(a)\}.$ This is kind of a trivial solution, though, and doesn't generalize well.
Two unary relations. At this point we try a different tactic. Let $M$ be a $\{U, V\}$-structure, where $U$ and $V$ are unary relation symbols. Our $\{R\}$-structure $N$ has domain $M\sqcup\{a, b_1, b_2\}$ - we add three new elements. $a$ is used to name $U$, and $\{b_1, b_2\}$ is used to name $V$. Specifically, we set $$R^N=\{(a, a)\}\cup\{(b_1, b_2), (b_2, (b_1)\}\cup\{(a, x): x\in M, M\models U(x)\}\cup\{(b_1, y): y\in M, M\models V(y)\}.$$ Note that $a$ is identifiable as the only element $R$-related to itself, and $\{b_1, b_2\}$ as the only pair of elements $R$-related to each other in both directions.
A ternary relation symbol.${}$A ternary relation symbol.${}$ This is the first nontrivial one, and the last one I'll do here. Suppose $M$ is an $\{S\}$-structure, where $S$ is a ternary relation symbol. The idea is as follows:
$N$ will have two main kinds of elements, standing for elements of $M$ and triples of elements of $M$.
In order to make sense of these, we'll need to be able to talk about the $i$th coordinate of a triple; and we'll need "yes" element to connect some triples to, in order to indicate of $S$ holds of that triple in $M$.
So we're going to need a bunch of "labels", as we had above.
Specifically, we let $N$ be the following: the domain of $N$ is $$M\sqcup M^3\sqcup (M^3\times \{1, 2, 3\})\sqcup \{a_1^1, a_1^2, a_2^2, a_1^3, a_2^3, a_3^3, a_1^4, a_2^4, a_3^4, a_4^4\}$$ and the relation $R^N$ is $$\{(a_i^k, a_j^k):i, j, k\in\{1, 2, 3, 4\}\}$$ $$\cup\{((p, q, r), (p, q, r, i)): p, q, r\in M, i\in\{1, 2, 3\}\}$$ $$\cup\{((p, q, r, i), a^i_j): p, q, r\in M, i, j\in\{1, 2, 3\}\}$$ $$\cup\{((p_1, p_2, p_3, i), p_i): i\in\{1, 2, 3\}\}$$ $$\cup\{((p, q, r), a_i^4): M\models S(p, q, r)\}.$$
This is very messy, but the basic idea is the same as the two-unary-relation example. Again, each of the sets $\{a_1^1\}$, $\{a_1^2, a_2^2\}$, $\{a_1^3, a_2^3, a_3^3\}$, $\{a_1^4, a_2^4, a_3^4, a_4^4\}$ is identifiable in $N$. The remaining objets of $N$ break down into two "main" sorts (the triples $M^3$ and the individuals $M$) and three "auxiliary" sorts (the extended triples connected to the first, second, and third block of $a$s respectively). $R$ behaves as a "two-step projection map" from $M^3$ to $M$: to tell what the $i$th coordinate of $(p, q, r)$ is, we look at what individual the element $(p, q, r, i)$ is connected to, and we can find $(p, q, r, i)$ given $(p, q, r)$ since the $i$th block of $a$s is identifiable. Finally, the fourth block of $a$s serves as the test for whether a triple satisfies $S$.