In misere tic tac toe on a 3x3 board with each player being x the second player will win. If the first player doesn't play the center square then the second player can (4-i,4-j,...) in response to any move (i,j) of the first player and the first player will be forced to form a line first. If the first player plays to the center square then the second player can play to the center of one of the rows or columns. Then there will be four squares left that the first player can move to without forming a line with two x's and losing. But whatever this move is it leave exactly one square left for the second player to move to and after that move is made every remaining move by the first player will result in a line with two spots filled with x's that the second player can fill in and win. So the second player will win.

In misere tic tac toe on a 3x3 board with each player being x the first player will win. the first player will play (2,2) then WLOG the second player will play (1,1) or (2,3) then if the second player has played (1,1) the first will play (2,3). And if the second player has played (2,3) the first will play (1,1). Now there are four squares in which the second player can move without losing: (1,2),(1,3),(3,2) and (3,1). If the second player plays (1,2) the first player plays (3,1) and on the next move the second player must form a line of three and the first player wins. If the second player plays (3,1) the first player plays (1,2) and on the next move the second player must form a line of three and the first player wins. If the second player plays (1,3) the first player plays (3,2) and on the next move the second player must form a line of three and the first player wins. If the second player plays (3,2) the first player plays (1,2) and on the next move the second player must form a line of three and the first player wins. But this exhausts all cases so the first player must win in this game.