My REU project was about this topic.
We found some interesting things about when osculating cubics are unique (plot twist: not always), as well as a formula for the osculating conic of a smooth plane curve (at a non-flex point). Here is the formula (copied from a software package I wrote, sorry for the mess),
Given
F(x,y):=(higher order terms) +a*x^4+b*x^3*y+c*x^2*y^2+d*x*y^3+e*y^4+f*x^3+g*x^2*y+h*x*y^2+i*y^3+j*x^2+k*x*y+l*y^2+m*x+n*y
The osculating conic of V(F) at (0,0) is given by
OscConic(a,b,c,d,e,f,g,h,i,j,k,l,m,n)=m*x+n*y+(j*x^2+k*x*y+l*y^2)+(-((-f)*n^3+g*m*n^2+(-h)*m^2*n+i*m^3)^2)/(j*n^2-k*m*n+l*m^2)^3*(m*x+n*y)^2+(a*n^4-b*m*n^3+c*m^2*n^2+(-d)*m^3*n+e*m^4)/(j*n^2-k*m*n+l*m^2)^2*(m*x+n*y)^2+(((x*(k*m-2*j*n)+y*(2*l*m-k*n))*((-f)*n^3+g*m*n^2+(-h)*m^2*n+i*m^3)-(x*(3*f*n^2-2*g*m*n+h*m^2)+y*(g*n^2-2*h*m*n+3*i*m^2))*(j*n^2-k*m*n+l*m^2))*(m*x+n*y))/(j*n^2-k*m*n+l*m^2)^2
The formula comes from the paper we wrote (look at Lemma 2.22 and 2.24) here