Let $M$ be a compact manifold and $\varphi : M \longrightarrow M$ be a diffeomorphism which is isotopic to the identity. Does there exist a vector field $ X $ on $M$ such that $\varphi$ is the flow at time $1$ of $X$? If that is not always the case, where does the obstruction for such a $\varphi$ to be a flow lives in ?