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Mar 20, 2013 at 11:21 comment added Ronnie Brown It seems to me you could also look at the use of the fundamental groupoid, since if $G$ acts on $X$ then it also acts on the fundamental groupoid $\pi_1 X$ and also on $\pi_1(X,A)$ provided $A$ is a union of orbits. For more details, and applications to determining $\pi_1 X/G$, see Chapter 11 of my book "Topology and Groupoids". These methods have not been extended to determine $\pi_n(X/G,A/G)$, $n \geqslant 2$, as far as I am aware. There could be interest in path models of $\pi_1(X,A).
Mar 20, 2013 at 9:17 vote accept Tom Sutton
Mar 20, 2013 at 9:17 comment added Tom Sutton Thanks very much for your answer Peter. I'd managed to confuse myself in a couple of places.
Mar 20, 2013 at 1:15 history answered Peter May CC BY-SA 3.0