I've split a paper once. I wasn't inclined to do it, but the paper was becoming huge so I was a bit worried -- 60+ pages, few people read papers that long. The other criterion was there was a natural way to split the paper into two useful papers. One turned out to be a "largely survey" 40+ page paper (sometimes. Sometimes it's tricky getting papers published when they have a lot of survey material), which concerned me at the time. This allowed for the main result to be a short 20+ page paper.
In general it comes down to a cost-benefit analysis. Size of the paper is a consideration. How interesting the results are, that matters. Some people go overboard on fragmentation of their papers. For example, if you're publishing more than 4 papers per year all on essentially the same topic, it leads to confusion among readers as to whatwhere your results appear where, and which papers depend on which.