An $\text{SL}(n,\mathbb{R})$-invariant metric on $\text{SL}(n,\mathbb{R})/\text{SO}(n)$: Since $M = \text{SL}(n,\mathbb{R})/\text{SO}(n)$$M=\text{SL}(n,\mathbb{R})/\text{SO}(n)$ is an irreducible Riemannian symmetric space (with nonpositive sectional curvature), it has, up to constant multiples, only one $\text{SL}(n,\mathbb{R})$-invariant Riemannian metric, and the associated $dist$ in this case is not entirely trivial to write down: We can identify each element $m = A\cdot \text{SO}(n)$ with its associated positive definite, unimodular symmetric matrix $s = \sigma(m) = AA^T$, and the formula for $dist(s_1,s_2)$ is as follows: Write
$$
\text{det}(ts_1-s_2) = (t-\lambda_1)(t-\lambda_2)\cdots(t-\lambda_n)
$$
where each $\lambda_i$ is positive and they satisfy $\lambda_1\lambda_2\cdots\lambda_n=1$. Then, up to a constant multiple, one has
$$
dist(s_1,s_2) = \left(\sum_{i=1}^n (\log\lambda_i)^2\right)^{1/2}.
$$
Obviously, writing this out as a function of the entries of $s_1$ and $s_2$ would not be easy. (Of course, this is just one example of the sort of metric that Paul gave; its distinguishing characteristic is that it is the $dist$ of a Riemannian metric, which is not true for Paul's specific example.)
A left-invariant metric on $\text{SL}(n,\mathbb{R})$:
Once an invariant metric on $M$ has been defined, one can use it to define a metric on $\text{SL}(n,\mathbb{R})$ itself: Suppose that $\delta:M\times M\to \mathbb{R}$ is such a metric and let $(s_1,\ldots,s_k)\in M\times M\times \cdots \times M$ ($k$ times)
be a $k$-tuple of symmetric matrices with the property that the simultaneous stabilizer of all of the $s_i$ in $\text{SL}(n,\mathbb{R})$ is the identity matrix. (I guess $k=3$ suffices to find such a $k$-tuple; $k=2$ does not.) Set
$$
dist(A,B) = \delta(As_1,Bs_1) + \delta(As_2,Bs_2) + \cdots + \delta(As_k,Bs_k).
$$
This defines a left-invariant metric on $\text{SL}(n,\mathbb{R})$. Note, however, that this is not derived from a Riemannian metric.
Computing $dist$ explicitly is nontrivial even in the case $n=2$. In this case, one has the fortunate circumstance that, unless $\det(v)>0$, there are no conjugate points along the geodesic $\gamma_v$, and, when $\det(v)>0$, the first conjugate point is at $t = \pi/\sqrt{\det(v)}$. However, determiningdescribing the exact cut locus of $I_n$ in ${\frak{sl}}(n,\mathbb{R})$ with respect to $ds^2$ does not seem to be trivial. Indeed, simple calculations show that the cut locus must be quite complicated. This does not seem to be a particularly good way to construct a left-invariant metric on $\text{SL}(2,\mathbb{R})$.
NB: I thought I had an explicit construction of a left-invariant metric on $\text{SL}(2,\mathbb{R})$ Nevertheless, butit's not hopeless. If I found a mistake in the calculationshave time, so I'm withdrawing it for more workI'll add a little note to this describing what one can say.