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Aug 30, 2012 at 21:52 vote accept Peter Muller
Aug 30, 2012 at 21:51 comment added Peter Muller Merci beaucoup.
Aug 30, 2012 at 16:00 comment added John Klein Yep. I was just posting it as an answer, but you beat me to the punch.
Aug 30, 2012 at 15:58 answer added John Klein timeline score: 13
Aug 30, 2012 at 15:57 comment added Oscar Randal-Williams @John: Such a map would lift to the universal cover of $X$, so have degree divisible by 120.
Aug 30, 2012 at 15:44 comment added John Klein My guess is that the $X =$ the Poincare homology sphere should provide a counterxample. If there were a map $S^3 \to X$ which induced a homology isomorphism, then this map is necessarily of degree one and we see that the fundamental class of $X$ is spherical. I don't see it at the moment, but this is very unlikely to be true.
Aug 30, 2012 at 15:31 comment added Hunter Brooks In extreme generality no - take the circle and map it onto the non-Hausdorff space "$[-1, 1]$ with two-origins" (by projecting vertically downward, mapping the north and south poles to the separate origins). This gives an isomorphism on all homology groups, but any map the other way is homotopic to a constant since the origins collapse.
Aug 30, 2012 at 15:07 history asked Peter Muller CC BY-SA 3.0