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Heaviside's operational calculus, used by electrical engineers to work with differential equations, predates its mathematically accepted justification by decades. The same can be said about Dirac's delta function, which is used together with it. Of course, to some extent the operational calculus is a repackaging of the Laplace transform, but that is not all there is to it.

One might argue that in this case mathematicians' splendid isolation worked the in the opposite direction.