For surfaces of constant mean curvature, it is alleged that Hopf thought that all compact CMC surfaces in $\mathbb{R}^3$ were round spheres. CMC surfaces are what you get if you have a soap film bounding a fixed volume, so after a childhood full of blowing bubbles this is a pretty reasonable thing to think. And it even happens to be mostly true: Hopf proved that immersed CMC spheres are round, and Alexandrov proved with a nice reflection argument that embedded CMC surfaces of any genus must actually be round spheres.