[Edited mostly to incorporate references etc. from Michael Zieve]
[Actually even less is known; the groups have been determined, but the polynomials, not quite, even in the polynomial case. See below. But this is tangential to the question at hand (albeit a fascinating tangent) because the ensuing argument is enough.][Naturally this result is not new, but I was still surprised to learn from Mike Zieve of its true age and pedigree: Hilbert (1892)! See below.]
where $\Delta_m := m^{(m-1)(m-3)}$ (and the sign depends on $n \bmod 4$). The formula for $q$ was obtained from the familiar expression $\pm \bigl( (n-1)^{n-1} A^n - n^n B^{n-1} \bigr)$ for the discriminant of the trinomial $x^n - Ax + B$. It follows that the numerator of (1) is$\pm$ the discriminant of $x^n - xy + (y-1) = (x-1) (p(x)-y)$ as a polynomial in $x$, whence (1) soon follows; substituting $y = nz/(nz-(n-1))$, and using the covariance of the discriminant under ${\rm PGL}_2$ together with the same trinomial formula, soon gives the claimed $\pm 2 \Delta_{n-1} \Delta_n$ (the factor of $2$ arises at the end from a double application of L'Hôpital's rule), QED. $\phantom.$
Here are some relevant references and additional information.
Polynomials with distinct critical values: This is in section 4.4 of Serre's Topics in Galois Theory (Boston: Jones & Bartlett 1992), as is the reference to Hilbert: "Ueber die irreduzibilität genzen rationalen Funktionen mit ganzzahligen Koeffizienten", J. reine angew. Math. ("Crelle's J.") 110, 104-129 (= Ges. Abh. II, 264-286). Serre gives such polynomials the suggestive name "Morse functions". M. Zieve also notes that a 1959 paper by Birch and Swinnerton-Dyer in Acta Arith. (MR0113844 (22 #4675)) attributes to Davenport the equivalent formulation
[The Galois group of $f(x) = y$] is the symmetric group if the discriminant of the discriminant of $f(x)-y$ does not vanish.
They call this a "more euphonious form"; that's a matter of taste, but at any rate it's a memorable formulation, and the one that ended up being used here.
Exceptional Galois groups of $p(x) = y$. The primitive groups that can occur are described by Peter Müller in a paper Primitive monodromy groups of polynomials. They are the symmetric and alternating groups, plus cyclic and dihedral groups (for polynomials equivalent to powers and Čebyšev), and a finite but substantial list of exceptional possibilities. It is hopeless to classify all cases of alternating Galois group. For the rest it can be done, but not easily. Some are exhibited by Cassou-Nogues and Couveignes in an Acta Arith. paper Factorisations explicites de $g(y)-h(z)$; most others were done by Mike Zieve himself; and the final case, polynomials of degree $23$ with Galois group the Mathieu group $M_{23}$, I computed only a few days ago after Mike noted it was still open (they're defined over the quadratic extension of ${\bf Q}(\sqrt{-23})$ of discriminant $3 \cdot 23^3$).
When $p$ is allowed to be a rational function, even the list of groups is not yet known. Mike notes that this "ties in with the 'genus zero program' initiated by Guralnick and Thompson" that was completed in a 2001 paper by Frohardt and Magaard in the Annals of Math. Thanks again to Mike Zieve for all this information.

