It's perhaps not in the spirit of Noble Academe, but increasingly I find myself looking at the editorial board for the journal. If there are people on it with whom I have actual personal professional contact (e.g. discussion at conference, or a prior exchange of work ideas) then -- other things being equal -- I'll be more likely to submit there.
(This is just for those of us whose primary concern is to aim for a decent journal but avoid the immediate "bin-as-intray". If your work is good enough, this shouldn't matter as much.)