Here is an example of a more conventional theorem: the homotopic invariance of De Rham cohomology. Differential forms and De Rham cohomology are well defined concept in diffeology, they apply in particular on space of paths of diffeological spaces, spaces of smooth maps, quotients etc.
We use here the Chain-Homotopy operator $$ K : \Omega^p(X) \to \Omega^{p-1}({\rm Paths}(X)) \quad \mbox{which satisfies} \quad K \circ d + d \circ K = \hat 1^* - \hat 0^*,$$ where $\hat 1$ and $\hat 0$ are the maps defined from ${\rm Paths}(X)$ to $X$ by $\hat 1(\gamma) = \gamma(1)$ and $\hat 0(\gamma) = \gamma(0)$.
Proposition Let $X$ and $X'$ be two diffeological spaces, let $f_0$ and $f_1$ be two homotopic smooth maps from $X$ to $X'$, let $\alpha$ be a closed $p$-form on $X'$. The pullbacks $f_0^*(\alpha)$ and $f_1^*(\alpha)$ are cohomologous.
Proof Let $\varphi : X \to {\rm Paths}(X')$ be the map defined by $\varphi(x) = [t \mapsto f_t(x)]$. The pullback by $\varphi$ of the identity $K(d\alpha) + d(K\alpha) = {\hat 1^*}(\alpha) - {\hat 0^*}(\alpha)$ gives $d(\varphi^*(K\alpha)) = f_1^*(\alpha) - f_0^*(\alpha)$. $\square$
This is an example of simplification/generalization of a classical theorem by short-cuting the proof through diffeology. Here also the space of paths of a diffeological space, and the Chain-Homotopy operator, are crucial. May be something more fundamental is hidden behind that. Enxin Wu a Dan Christensen student is working on a possible Quillen model based on diffeology, it will give maybe some lighting on this question?

