Let $M=C^*_\lambda(G)''$ be group von Neumann algebra of $G$. The the condition above implies:
$d(T, M')\leq C ||ad(T)|_{M}||$ for every $T\in B(l^2 G)$. The last inequality is equivalent to saying that every derivation of $M$ into $B(l^2 G)$ is inner.
Edit: the above inequality is satisfied automatically (was clarified to me by Stuart White).
It is known that if $M\subset B(H)$ has a cyclic vector, then every bounded derivation from $M$ into $B(H)$ is inner [E. Christensen, Extensions of derivations II, Math. Scand., 1982]. Thus [Christensen, op cit, Cor 5.4] we have
$d(T,M')\leq 3/2\|(\mathrm{ad}| T)_{M}\|$
for every $T\in B(l^2 G)$.

