Here is a way to realize a positive version of the
phenomenon:
Theorem. If the CH holds, then there is a coloring
of $\mathbb{R}^3$ into six colors, such that every line
parallel to one of the coordinate axes is almost
monochromatic, meaning that it uses only one color for all
but countably many points. (And each major axis direction will give rise to distinct two of the six colors.) Furthermore, the coloring on every plane parallel to the
principal axis planes uses only two colors (except on countably many pointslines) and exhibits the two-dimensional
Sierpinski property mentioned in the question.
The proof idea is simply to extend the two-dimensional
proof idea to three dimensions. Namely, if CH holds, then
well-order the reals in order type $\omega_1$. In the two
dimensional case, we may color a pair $(x,y)$ black or
white according to whether $x\lt y$ or not with respect to
that well-ordering. Every vertical line is almost black,
since all but countably many $y$ are above any given $x$ in
the well-order, and every horizontal line is almost white,
since only countably many $x$ are below any fixed $y$.
In three dimensions, we color a triple $(x,y,z)$ according
to the order type of the triple with respect to the
well-order, that is, according to whether $x\leq y\leq z$
or $y\leq x\leq z$ and so on, using the well-order relation here (not the usual order on $\mathbb{R}$), for each of the six
possibilities. (We may use the first occurring case when the
coordinates are not distinct, since these exceptional cases don't affect the final property.) Any line parallel to one of the principal
axes corresponds to fixing two of the variables. The third
variable will range over all the remaining reals, but all
but countably many of these reals will have the same
relation to those two fixed reals. For example, if we fix
$x$ and $y$, then for all $z$ above both of them in the
well-order, the order type of $(x,y,z)$ will be the same.
And it is the same if we fix $x$ and $z$ or $y$ and $z$.
Thus, all such lines are monochromatic outside a countable
set.
It follows that all the planes parallel to the principal
axis planes will exhibit the two-dimensional coloring
property mentioned in the question.
A similar phenomenon arises in every higher dimension
$\mathbb{R}^n$, simply by using more colors: one should
simply color $(x_1,\ldots,x_n)$ by the order type of these
elements with respect to the fixed well-ordering.
Finally, let me say that one can avoid the CH assumption in
this entire discussion, if one simply re-interprets the
phrase "almost all" as meaning "fewer than continuum many"
rather than "countably many". One can achieve this by
well-ordering the reals in order type continuum rather than
order type $\omega_1$, and then applying the same argument.
The crucial fact is that every initial segment of such a
well-ordering has size less than the continuum.