Since Colin's comment indicates that this is not about $\LaTeX$ and some answers have given good specific advice I want to throw in a more abstract answer:
• BUT do it in such a way that anyone with access to the source (e.g. journal, website) can easily modify the layout (e.g. in $\LaTeX$ make sure redefining your environment is easy, maybe even via options for your own sty file, for a website use good css)