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"Automorphisms of the symmetric group $S_n$ are inner (that is, each one is of the form $x \to axa^{-1}$ for some $a \in S_n$)" is a popular misconception, false for nontrivial reasons when $n=6$. That is both an easy mistake to make and important conceptually as an early hint of the complexities and special combinatorics that arise in finite group theory. Many people make it through a first class in group theory without understanding that something different happens for $S_6$ and in doing so have missed an important piece of the the big picture, as far as finite groups are concerned.

It is easy to implicitly or explicitly acquire this belief, because:

1. those really are all the automorphisms for $n$ other than 6, and

2. the inner automorphisms are used so often, for all values of $n$ (or $n>2$) without distinguishing any specific case as unusual.

3. $S_n$ behaves in many ways as a family of similar groups rather than a list of individual groups with their own diverse features. A typical proof might show some property of $S_n$ by induction on $n$, starting from a small value such as $n=1$ for basic properties, or $n=3$ to assure noncommutativity. Apart from the classification of symmetric group automorphisms itself (exposure to which would be an explicit articulation and correction of the false belief), these arguments never start as high as $n=7$ and I don't know of any that distinguish $n=6$ or some equivalent case as a lone nontrivial exception. So it is easy to get the idea of more uniformity in the $S_n$ than really exists.

In essence, there are no obvious clues in the environment that $n=6$ might be special, and a number of indicators that no special case should exist at all.