This is probably well know, and maybe even trivial, but not to me. Consider for concreteness the subgroup $$ \pm\Gamma_0(3)=\left\{\begin{pmatrix}a & b \\ c & d\end{pmatrix}:\;a,b,c,d\in\mathbb{Z},ad-bc=\pm1, c\equiv 0\pmod 3\right\} $$ of $GL_2(\mathbb{Z})$. This has of course index 4 in $GL_2(\mathbb{Z})$. The first (possibly completely ridiculous) question is

Does $\pm\Gamma_0(3)$ contain a subgroup isomorphic to $GL_2(\mathbb{Z})$?

It's not even obvious to me that the two are not isomorphic as abstract groups. The second question is

Does $GL_2(\mathbb{Z})$ contain subgroups that are isomorphic to $\pm\Gamma_0(3)$ with finite index other than 4? If the answer is yes, then what is the least common multiple of all such indices? E.g. is there a subgroup of index 3 (or 5, or 7, or...) in $GL_2(\mathbb{Z})$ isomorphic to $\pm\Gamma_0(3)$? Or will all such indices be multiples of 4?

An answer or technique that is applicable to other congruence subgroups and to other values of 2 would be a great bonus, but for now I would happily settle for an answer to this concrete question.