Let $X$ be a topological space and let $\mathcal{F}$ and $\mathcal{G}$ be two sheaves over $X$.
Of course, if one has a morphism $f : \mathcal{F} \to \mathcal{G}$ such that for all $x\in X$, $f_x : \mathcal{F}_x \to \mathcal{G}_x$ is an isomorphism, then it is known that $f$ itself is an isomorphism.
My question is the following: if we don't have such a morphism $f$, but if we know that for all $x\in X$, $\mathcal{F}_x$ and $\mathcal{G}_x$ are isomorphic, is it true that $\mathcal{F}$ and $\mathcal{G}$ are isomorphic ?